2nd Grenadier Guards F.C. were an English football team that played in the London League Division One during the 1897-98 season, finishing ninth of nine. In that season champions Thames Ironworks F.C. recorded their equal biggest win of the season against the 2nd Grenadier Guards, beating them 5-1.
They joined the Southern Football League in 1908 and finished fourth of nine in Division Two. They withdrew from the league after this season.